Vitamin C Benefits Infants’ Lungs Damaged By Smoking During Pregnancy

Vitamin C may reduce the harm done to lungs in infants born to mothers who smoke during their pregnancy. These are the results of a new study published in the American Thoracic Society’s ‘American Journal of Respiratory and Critical Care Medicine’. 

To this end, a co-author of the study, Cindy T. McEvoy said that a relatively low dosage of vitamin C may be a safe intervention to help lung health of millions of infants worldwide, though, helping mothers quit smoking should remain the primary goal for health professionals and public health officials. 

According to the researchers, the study results support the hypothesis that oxidative stress caused by cigarette smoking reduces the amount of ascorbic acid, a component of vitamin C, available to the body. McEvoy and her co-authors reported that at three months of age, the infants whose mothers took 500 mg of vitamin C in addition to their prenatal vitamin had significantly better forced expiratory flows (FEFs).

FEFs measure how fast air can be exhaled from the lung and are an important measure of lung function because they can detect airway obstruction. Similarly, they discovered an association between the infant FEFs and a genetic variant some of the mothers possessed that appeared to amplify the negative impact of nicotine on the babies before they were born. 

McEvoy said finding a way to help infants exposed to smoking and nicotine in utero recognises the unique dangers posed by a highly advertised, addictive product and the lifetime effects on offspring who did not choose to be exposed.

Previous studies show that the primary effects of maternal smoking on offspring lung function and health are decreases in forced expiratory flows, decreased passive respiratory compliance, increased hospitalisation for respiratory infections, and an increased prevalence of childhood wheeze and asthma.

Nicotine appears to be the responsible component of tobacco smoke that affects lung development, and some of the effects of maternal smoking on lung development can be prevented by supplemental vitamin C. In the current study, 251 pregnant women who smoked were randomly assigned at 13 to 23 weeks of gestation to either receive vitamin C (125 women) or a placebo (126 women). 

Smoking was defined as having had one or more cigarettes in the last week. All participants received smoking cessation counselling throughout the study, and about 10 per cent of the women quit smoking during the study. At the time they enrolled in the study, the women had lower levels of ascorbic acid that have been reported among women who do not smoke. However, those levels rose in study participants who received vitamin C to become comparable to women who do not smoke.

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People With Asthma At Higher Risk Of Becoming Obese – Study

Obesity is known to be a risk factor for developing asthma but a new study shows that the reverse is also true: people with asthma are more likely to go on to become obese.

The new research, presented at the European Respiratory Society International Congress, indicates that those who develop asthma as adults and those who have non-allergic asthma are at the greatest risk of obesity.

The team behind the research say it suggests the relationship between asthma and obesity is more complex than previously thought and more research is needed to better understand and tackle these two growing health challenges.

The research was presented by Dr Subhabrata Moitra, a European Respiratory Society research fellow at ISGlobal — the Barcelona Institute for Global Health (a centre supported by the “la Caixa” Foundation), Spain. He explained: “We already know that obesity can be a trigger for asthma, perhaps via a physiological, metabolic or inflammatory change.

“Until now there has been very little research on whether the reverse is true — whether asthma can lead to obesity. In this study, we have enough people and we have followed them for long enough to observe the relationship between these two conditions.”

The research was part of the European Community Respiratory Health Survey and included 8,618 people from 12 countries who were not obese at the start of the research. This means they all had a body mass index of less than 30kg/m2.

Participants were considered to have asthma if they reported ever having asthma and had an asthma attack or were woken up by an attack of shortness of breath in the previous 12 months, or if they were currently taking asthma medication.

The study began recruiting in the 1990s, and participants were followed up after ten years and again after 20 years. The researchers examined the relationships between having asthma at the start of the study and the likelihood of being obese ten years later. They also studied people who had developed asthma after ten years in the study and their risk of obesity by 20 years. Researchers took other risk factors into consideration, including age, sex, country and physical activity.

They found that 10.2% of people with asthma at the start of the study had become obese ten years on. Among people who did not have asthma, 7.7% were obese ten years later.

The increase in the risk of obesity was even greater in people whose asthma began in adulthood. It was also greater in people who had asthma but did not suffer with allergies.

Dr Moitra added: “By following a large number of study participants over two decades, we have been able to observe how having asthma increases a person’s risk of going on to become obese, especially if their asthma begins in adulthood or if they have asthma but no allergies.

“Our findings suggest the relationship between the two conditions is more complicated than we previously realised. It’s important that we do more work to pick this apart. For example, we do not know why having asthma increases the risk of developing obesity or whether different asthma treatments have any effect on this risk.”

Professor Guy Brusselle from Ghent University in Belgium is Chair of the European Respiratory Society Science Council and was not involved in the study. He said: “With the right medication, many people with asthma gain good control of their symptoms. However, there is no cure for asthma and there is still a lot we do not know about its causes and its effects on the rest of the body. This research is an important step in helping us untangle the relationship between obesity and asthma but it also raises new questions about why the two are linked and what can be done to help patients.”

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Study Links Body Fats To Breast Cancer

Older women with excess body fat, even if they have what’s considered a normal body-mass index (BMI), could be at greater risk for breast cancer. Findings of a new study suggesting this were published in the medical journal ‘JAMA Oncology’. According to the authors of the study, having excess body fat, even when one has a normal BMI, is associated with an increased risk for breast cancer.

A ‘normal’ BMI is considered to be between 18.5 and 24.9, according to the study. One of the author’s study and director of cancer prevention at the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine in New York, Dr. Andrew Dannenberg, said, “We do find that excess body fat in those who are post-menopausal with a normal BMI is associated with about a doubling in the risk of estrogendependent breast cancer.”

A cancer is called estrogen- receptor-positive (or ER+) if it has receptors for estrogen. This suggests that the cancer cells, like normal breast cells, may receive signals from estrogen that could promote their growth. The cancer is progesteronereceptor- positive (PR+) if it has progesterone receptors. Cancer is the second leading cause of death globally, and is responsible for an estimated 9.6 million deaths in 2018. Globally, about one in sixdeaths is due to cancer.

Approximately 70 per cent of deaths from cancer occur in low- and middle-income countries. According World Health Organisation (WHO), over 100,000 Nigerians are diagnosed with cancer annually, and about 80,000 die from the disease, averaging 240 Nigerians every day or 10 Nigerians every hour. The research team found that a five-kilogram (11-pound) increase in wholebody fat mass was associated with a 35 per cent increased risk of this kind of breast cancer.

A five-kilogram increase in fat mass of the trunk was associated with a 56 per cent increase in risk. Trunk fat is “defined by the fat contained in the torso apart from head and limbs,” according to the study. The study also found that for invasive breast cancer, which has spread into the surrounding breast tissue, a five-kilogram increase in whole-body fat mass was related to a 28 per cent risk increase. The same increase in trunk fat was tied to a 46 per cent increase in the risk of invasive breast cancer.

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Genital Itching May be First Signs Of Diabete - Expert

A health expert, Dr Joke Adeleye, has said that the first sign of diabetes in some persons could just be genital itching or a recurrent boil.

Dr Adeleye made this disclosure at the 2018 World Diabetes Day celebration organised by the UCH, Ibadan Diabetes Care team and Diabetes Association of Nigeria, Oyo State, with the theme “the family and diabetes.”

The diabetologist stated that itching in the genital area both for men and women could be a common sign of diabetes even when they have not noticed the other typical signs of diabetes such excessive passage of urine, feeling unduly thirsty, and losing weight despite a healthy balanced diet.

Adeleye, who noted that diabetes in some individuals is without symptoms, added that the vaginal itching in the woman may also be accompanied with a thick discharge.

The expert stated that itching of the skin, particularly around the genitals, until proven otherwise may be pointers to the fact that the blood glucose levels are high.

“So if you notice something unusual, particularly if you are an adult, you should get tested, even if such things are noticed in children, they also should get tested.”

 

Dr Adeleye urged that every adult after the age of 40 years should have their blood sugar checked at least one in three years.

“However, if you have a family history of diabetes, a young person who has siblings or parents with diabetes or risk factors for diabetes such as overweight, high blood cholesterol and blood pressure, request to have a blood sugar test done every year even if you do not feel unwell or have symptoms of diabetes,” she added.

Earlier, Professor Adesoji Fasanmade, the chairman at the event expressed concern on the increasing cases of diabetes in Nigeria, which he linked with lifestyle, diet and poor exercising.

Fasanmade, noting that of every 100 adults in Nigeria, 8 persons now live with diabetes but only half of them know they have the disease, urged Nigerians to be more proactive about their health.

Chairman, Diabetes Association of Nigeria, Oyo State, Chief Emmanuel Adeyinka, linked the upsurge in adult and juvenile diabetes to the aggressive and relentless advertisement by fast food vendors, urging parents to always serve children home balanced diet, fruits, vegetables and adequate water.

At the event had 250 persons tested for diabetes and a road show to create awareness about the disease.

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Too Much Sleep Could Lead To Cardiovascular Disease And Death

The recommended hours of sleep for adults to achieve healthy living is six to eight hours daily but experts said sleeping more than those hours could be linked to increased risk of cardiovascular (CVD) disease and premature death.

According to the findings of a new study published in the ‘European Heart Journal’, compared with people who slept six to eight hours a night, those who slept eight to nine hours had a five per cent increased risk for CVD or death. Lead author of the study Chuangshi Wang who is a doctoral student at the McMaster University in Hamilton, Ontario, Canada, urged adults to get enough sleep — that is, six to eight hours a day.

“But if you sleep more than nine hours a day, you may want to visit a doctor to check your overall health,” he added.” People who slept nine to 10 hours had a 17 per cent increased risk, and those who slept more than 10 hours increased their risk by 41 per cent.

The researchers also found a nine per cent increased risk in people who slept less than six hours, but that difference was not statistically significant. Daytime naps also increased the risk for cardiovascular events, but only in people who slept more than six hours a night.

The researchers controlled for age, body mass index, physical activity, diabetes, depression, smoking, alcohol consumption and many other health and behavioral characteristics.

The researchers gathered health and lifestyle information, including self-reported sleep data, on 116,632 people in 21 countries, followed them up for over eight years and recorded 4,381 deaths and 4,365 major CVD events. CVD events refer to any incident that may cause damage to the heart muscle. The heart is a busy organ, constantly pumping blood filled with oxygen and nutrients through your arteries, into the heart muscle (myocardium). Any interruption of blood flow will lead to an injury, or infarction.

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Prevent Stroke, Anemia And Other Diseases With Regular Diet Of Plantain

Plantains, also known as plátanos, are closely related cultivars of fruit or dessert banana. In general, they are treated as vegetables in the kitchen much like fellow tropical produces such as potatoes, taro, breadfruit, yam, sweet potatoes, etc. Indeed, plátano are one of the staple sources of carbohydrates for larger populations. Plantain is so rich that it is consumed in almost every part of the world.

Plantain is quite different from dessert banana, being taller and larger and more drought tolerant. It is a perennial herbaceous plant that develops from the underground rhizome. Like bananas, it too flourishes well under tropical moisture-rich, humid low-lying farmlands. At maturity, the rhizome gives rise to flower (inflorescence) that is carried up along its smooth, elongated, un-branched stem, piercing through the center of pseudo-stem, finally emerging out at the top in between its leafy clusters.

Plantain relatively has more calories weight for weight than that in the table bananas. 100g plantain holds about 122 calories, while dessert banana has only 89 calories. Indeed, they are very reliable sources of starch and energy; ensuring food security for millions of inhabitants worldwide. It contains 2.3 g of dietary fiber per 100 g (6% of DRA per 100 g). Adequate amount of dietary-fiber in the food helps normal bowel movements, thereby reducing constipation problems.

Fresh plátanos have more vitamin C than bananas. 100g provide 18.4 mg or 31% of daily required levels of this vitamin. Consumption of foods rich in vitamin-C helps the body develop resistance against infectious agents and scavenge harmful oxygen-free radicals. However, boiling and cooking destroys much of this vitamin in plantains. Plantains carry more vitamin A than bananas. 100 g fresh ripe plantains contain 1127 IU or 37.5% of daily required levels of this vitamin.

As in bananas, they too are rich sources of B-complex vitamins, particularly high in vitamin-B6 (pyridoxine). Pyridoxine is an important B-complex vitamin that has a beneficial role in the treatment of neuritis, anemia, and to decrease homocystine (one of the causative factors for coronary artery disease (CHD) and (stroke episodes) levels in the body. In addition, the fruit contains moderate levels of folates, niacin, riboflavin and thiamin.

They also provide adequate levels of minerals such as iron, magnesium, and phosphorous. Magnesium is essential for bone strengthening and has a cardiac-protective role as well. Fresh plantains have more potassium than bananas. 100 g fruit provides 499 mg of potassium (358 mg per 100 g for bananas). Potassium is an important component of cell and body fluids that helps control heart rate and blood pressure, countering negative effects of sodium.

At maturity, plantains are generally harvested unripe and right away carried to the market for sale. Look for firm, mature, deep green, well-formed plantains that feel heavy in hand. Do not buy overripe, damaged, split fruits, as they stay poor. Once at home, store them open at room temperature for up to 4-5 days. Once ripen, plantains too, like bananas, are very fragile and show signs of decay in short time span.

Plantains are inedible raw and should be eaten only after cooked. To prepare, just wash the raw fruit in cold water and mop dry using paper cloth. Using a paring knife, trim either ends. Then, cut the fruit into short lengths, split the skin superficially along the ridge and peel the skin gently away from the flesh to get firm flesh inside. Oftentimes, the whole fruit may be barbequed with its skin. Otherwise, its peeled flesh may be cut into thin slices, grated, chunks treated much like potatoes in many traditional African and West-Indian cuisine.

Plantains make delicious savory recipes, used in place of potatoes in grills, mashed, bake, or fries. In South-Indian Kerala state, plantain chips (vaazhakka upperi) seasoned with salt and pepper, is a popular snack. Tostones (plátano, fried twice), prepared in a similar way are again a popular snacks in the Caribbean and Latin Americas. Its flower head (inflorescence) and interior icicle-white, tender stem (vazhai thandu in Malayalam) too are eaten in various kinds of recipes in South-Asian regions.

Sopa de plátano is a popular Caribbean soup preparation that used green platanos, garlic, cilantro, and cheese. Mashed plantain served with fried onions is a national breakfast dish of Dominican Republic. Mashed platanos are served with rice, eggs, beans, poultry, fish, etc., in these regions. In some African communities, plantain is pounded into a form in which it is eaten with stews or soups such as egusi soup or okro soup.

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