New Malaria Vaccine Offers 100 Per cent Protection In Clinical Trial

Scientists have discovered an effective vaccine that offers up to 100 per cent protection from malaria. German researchers at the University of Tübingen in collaboration with the biotech company, Sanaria Incorporated, have demonstrated in a clinical trial that a new vaccine for malaria called Sanaria PfSPZ-CVac has been up to 100 per cent effective when assessed at 10 weeks after last dose of vaccine.
With this discovery, Nigeria can save over 300,000 lives lost to malaria yearly and over N480 billion spent on the treatment and control of the parasite annually. The search for a vaccine has been going on for more than a century. An effective vaccine would make it easier to control malaria; vaccination campaigns could be conducted in severely affected areas to eliminate the pathogen. Such a vaccine could also help to stop the spread of resistance to the treatment, and to better protect travellers.
Details of the research results were published yesterday in the latest edition of the journal Nature. Tübingen University is a public research institution located in the city of Tübingen, Baden-Württemberg. It is one of Germany’s most famous universities in the areas of medicine, natural sciences, and the humanities.
Malaria is an ailment that is quite endemic in tropical Africa, especially in Nigeria. A cross-sectional community-based study was conducted on 551 participants from five local government areas in Kano State. Blood samples were collected and examined for the presence of Plasmodium species by rapid diagnostic test (RDT), Giemsa-stained thin and thick blood films, and PCR. Moreover, demographic, socioeconomic, and environmental information as well as KAP data were collected using a pre-tested questionnaire.
A total of 334 (60.6 %) participants were found positive for Plasmodium falciparum. The prevalence differed significantly by age group (p < 0.01), but not by gender or location. A multivariate analysis showed that malaria was associated significantly with being aged 12 years or older, having a low household family income, not using insecticide treated nets (ITNs), and having no toilets in the house. Overall, 95.6 % of the respondents had prior knowledge about malaria, and 79.7, 87.6 and 95.7 % of them knew about the transmission, symptoms, and prevention of malaria, respectively. The majority (93.4 %) of the respondents considered malaria a serious disease. Although 79.5 % of the respondents had at least one ITN in their household, utilization rate of ITNs was 49.5 %. Significant associations between the respondents’ knowledge concerning malaria and their age, gender, education, and household monthly income were reported.
With the discovery of the new vaccine, experts say a new done is about to break for Nigerian and other tropical countries plagued by malaria. It is believed that this new era will reverse the high mortality associated with the disease.

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